Science

Research, machine learning, and scientific insights

Random Forests vs Gaussian Processes: A Practical Maths-First Comparison

Random Forests and Gaussian Processes (GPs) are both powerful non‑parametric models (models that don’t fix a single, limited functional form in advance) for regression and classification, but they come from very different mathematical worlds.

Read More

Understanding Molecular Dynamics Simulations

Molecular dynamics simulations are powerful computational tools for understanding the dynamic behavior of particles over time. This post explores the fundamentals of MD simulations, from the statistical mechanics foundations to practical implementation using the Verlet algorithm.

Read More

Understanding Oligonucleotide Impurities Across Nucleotide Modifications

Exploring the most common chemical impurities in oligonucleotide synthesis across different nucleotide modification families, with interactive visualizations showing chemical structures and formation mechanisms.

Read More

Oligonucleotide Manufacturing

Last week, I had the privilege of presenting at the Innovation in Oligonucleotide Manufacturing Symposium hosted by CPI at the Medicines Manufacturing Innovation Centre in Glasgow.

Read More